Purpose : This study aims to clarify the correlation between postprandial hypotension (PPH) and autonomic
nervous activity in elderly people with dementia.
Method : We examined the autonomic nervous activities of ambulatory patients by measuring their blood pressure, pulse and finger plethysmogram before and after meals for five days.
Results : There were 11 male and 20 female subjects with a median age of 85.42 ± 6.36. We had 23 patients
with AD, six with DLB, one with Wernicke-Korsakoff, and one with cerebrovascular dementia. 61 percent of the subjects showed symptoms of PPH. 70 percent of the patients with AD showed symptoms of PPH. The value of Ln (LF / HF)with PPH was 0.93 ± 0.24 before meal and 0.81 ± 0.17 (p<0.05) after meal, while the average value of Ln(LF / HF)without PPH was 0.93 ± 0.28 before meal and 0.92 ± 0.26 after meal. The comparison showed no significant differences.
Discussion : No disparity was found in autonomic nervous activities among patients without PPH symptoms.
It is suggested that PPH affects sympathetic nerve activity since we observed a significant decrease of sympathetic nerve activities after meals.
雑誌名
日本認知症ケア学会誌 = Journal of Japanese Society for Dementia Care
雑誌名(英)
日本認知症ケア学会誌 = Journal of Japanese Society for Dementia Care
認知症高齢者の食事性低血圧と自律神経活動との関連
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