@article{oai:jrckicn.repo.nii.ac.jp:00000869, author = {西村, 伸子 and NISHIMURA, Nobuko and KAWASAKI, Mikiko and 川﨑, 幹子 and 藤枝, 史郎 and FUJIEDA, Shiro and 岡村, 美智子 and OKAMURA, Michiko}, issue = {4}, journal = {日本認知症ケア学会誌 = Journal of Japanese Society for Dementia Care, 日本認知症ケア学会誌 = Journal of Japanese Society for Dementia Care}, month = {}, note = {http://ci.nii.ac.jp/naid/40022172208, application/pdf, 【目的】認知症高齢者の食事性低血圧(PPH)と自律神経活動の関連と,PPHの発現頻度,自律神経活動との関連を明らかにする.【方法】歩行可能な入院中の認知症高齢者を対象に,食前と食後の血圧,脈拍,指尖脈波を用いた自律神経活動測定を,座位にて5日間実施した,【結果】対象者は男性11人,女性20人,合計31人で,平均年齢85.42±6.36歳であった.病名別ではアルツハイマー型認知症(AD)23人,レビー小体型認知症(DLB)6人,ウェルニッケ・コルサコフ症候群1人,脳血管性認知症1人であった.対象者の61%にPPHの発現があった.ADの70%にPPHの発現があった.PPH発現時のLn(LF/HF)は食前0.93±0.24,食後0.81±0.17(p<0.05)で有意差があった.PPHの発現なし時のLn(LF/HF)の平均値は食前0.93±0.28,食後0.92±0.26であり,有意差はなかった.【考察】PPH発現のケースでは食前・後のLn(LF/HF)に差があり,PPH発現なしではLn(LF/HF)に差がないことから,PPHの発現ケースには心臓交感神経活動が食前と比して食後に有意に減弱しており,交感神経活動にPPHが影響していることが示唆された., Purpose : This study aims to clarify the correlation between postprandial hypotension (PPH) and autonomic nervous activity in elderly people with dementia. Method : We examined the autonomic nervous activities of ambulatory patients by measuring their blood pressure, pulse and finger plethysmogram before and after meals for five days. Results : There were 11 male and 20 female subjects with a median age of 85.42 ± 6.36. We had 23 patients with AD, six with DLB, one with Wernicke-Korsakoff, and one with cerebrovascular dementia. 61 percent of the subjects showed symptoms of PPH. 70 percent of the patients with AD showed symptoms of PPH. The value of Ln (LF / HF)with PPH was 0.93 ± 0.24 before meal and 0.81 ± 0.17 (p<0.05) after meal, while the average value of Ln(LF / HF)without PPH was 0.93 ± 0.28 before meal and 0.92 ± 0.26 after meal. The comparison showed no significant differences. Discussion : No disparity was found in autonomic nervous activities among patients without PPH symptoms. It is suggested that PPH affects sympathetic nerve activity since we observed a significant decrease of sympathetic nerve activities after meals.}, pages = {840--846}, title = {認知症高齢者の食事性低血圧と自律神経活動との関連}, volume = {18}, year = {2020}, yomi = {ニシムラ, ノブコ and カワサキ, ミキコ and フジエダ, シロウ and オカムラ, ミチコ} }