@article{oai:jrckicn.repo.nii.ac.jp:00000859, author = {井上, 茂亮 and INOUE, Shigeaki and 畠山, 淳司 and HATAKEYAMA, Junji and 近藤, 豊 and KONDO, Yutaka and 一二三, 亨 and HIFUMI, Toru and SAKURAMOTO, Hideaki and 櫻本, 秀明 and 川崎, 達也 and KAWASAKI, Tatsuya and 對東, 俊介 and TAITO, Shunsuke and 中村, 謙介 and NAKAMURA, Kensuke and UNOKI, Takeshi and 卯野木, 健 and 河合, 佑亮 and KAWAI, Yusuke and 剱持, 雄二 and KENMOTSU, Yuji and 齋藤, 雅史 and SAITO, Masafumi and 山川, 一馬 and YAMAKAWA, Kazuma and 西田, 修 and NISHIDA, Osamu}, issue = {3}, journal = {Acute Medicine & Surgery}, month = {Jul}, note = {application/pdf, Expanding elderly populations are a major social challenge in advanced countries worldwide and have led to a rapid increase in the number of elderly patients in intensive care units (ICUs). Innovative advances in medical technology have enabled lifesaving of patients in ICUs, but there remain various problems to improve their long-term prognoses. Post-intensive care syndrome (PICS) refers to physical, cognition, and mental impairments that occur during ICU stay, after ICU discharge or hospital discharge, as well as the long-term prognosis of ICU patients. Its concept also applies to pediatric patients (PICS-p) and the mental status of their family (PICS-F). Intensive care unit-acquired weakness, a syndrome characterized by acute symmetrical limb muscle weakness after ICU admission, belongs to physical impairments in three domains of PICS. Prevention of PICS requires performance of the ABCDEFGH bundle, which incorporates the prevention of delirium, early rehabilitation, family intervention, and follow-up from the time of ICU admission to the time of discharge. Diary, nutrition, nursing care, and environmental management for healing are also important in the prevention of PICS. This review outlines the pathophysiology, prevention, and future directions of PICS.}, pages = {233--246}, title = {Post-intensive care syndrome: its pathophysiology, prevention, and future directions}, volume = {6}, year = {2019}, yomi = {イノウエ, シゲアキ and ハタケヤマ, ジュンジ and コンドウ, ユタカ and ヒフミ, トオル and サクラモト, ヒデアキ and カワサキ, タツヤ and タイトウ, シュンスケ and ナカムラ, ケンスケ and ウノキ, タケシ and カワイ, ユウスケ and ケンモツ, ユウジ and サイトウ, マサフミ and ヤマカワ, カズマ and ニシダ, オサム} }