{"created":"2024-01-19T07:44:09.127875+00:00","id":2000018,"links":{},"metadata":{"_buckets":{"deposit":"0aaa7017-f8f2-4293-9fef-f50ec7053fc3"},"_deposit":{"created_by":14,"id":"2000018","owner":"14","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"2000018"},"status":"published"},"_oai":{"id":"oai:jrckicn.repo.nii.ac.jp:02000018","sets":["15"]},"author_link":["1697","1616","1650","1617","1653"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"23779608231206700","bibliographicVolumeNumber":"9","bibliographic_titles":[{"bibliographic_title":"SAGE Open Nursing","bibliographic_titleLang":"en"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: The international guidelines recommend light sedation management for patients receiving mechanical ventilation. One of the benefits of light sedation management during mechanical ventilation is the preservation of spontaneous breathing, which leads to improved gas-exchange and patient outcomes. Conversely, recent experimental animal studies have suggested that strong spontaneous breathing effort may cause worsening of lung injury, especially in severe lung injury cases. The association between depth of sedation and patient outcomes may depend on the severity of lung injury.\nObjective: This study aimed to describe the patients’ clinical outcomes under deep or light sedation during the first 48 h of mechanical ventilation and investigate the association of light sedation on patient outcomes for each severity of lung injury.\nMethods: The researchers performed a retrospective observational study at a university hospital in Japan. Patients aged ≥20 years, who received mechanical ventilation for at least 48 h were enrolled.\nResults: A total of 413 patient cases were analyzed. Light sedation was associated with significantly shorter 28-day ventilator-free days compared with deep sedation in patients with severe lung injury (0 [IQR 0–5] days vs. 16 [0–19] days, P = .038). In the groups of patients with moderate and mild lung injury, the sedation depth was not associated with ventilator-free days. After adjusting for the positive end-expiratory pressure and APACHE II score, it was found that light sedation decreased the number of ventilator-free days in patients with severe lung injury (−10.8 days, 95% CI −19.2 to −2.5, P = .012).\nConclusion: Early light sedation for severe lung injury may be associated with fewer ventilator-free days.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"SAGE Publications","subitem_publisher_language":"en"}]},"item_10001_relation_18":{"attribute_name":"他の資源との関係","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"en","subitem_relation_name_text":"Cite article: Hatozaki C, Sakuramoto H, Ouchi A, Shimojo N, Inoue Y. Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury. SAGE Open Nursing. 2023;9. doi:10.1177/23779608231206761"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1177/23779608231206761","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2023.","subitem_rights_language":"en"},{"subitem_rights":"This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2377-9608","subitem_source_identifier_type":"EISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HATOZAKI, Chie","creatorNameLang":"en"},{"creatorName":"鳩崎, 千絵","creatorNameLang":"ja"},{"creatorName":"ハトザキ, チエ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SAKURAMOTO, Hideaki","creatorNameLang":"en"},{"creatorName":"櫻本, 秀明","creatorNameLang":"ja"},{"creatorName":"サクラモト, ヒデアキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"大内, 玲","creatorNameLang":"ja"},{"creatorName":"OUCHI, Akira","creatorNameLang":"en"},{"creatorName":"オオウチ, アキラ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SIMOJO, Nobutake","creatorNameLang":"en"},{"creatorName":"下條, 信威","creatorNameLang":"ja"},{"creatorName":"シモジョウ, ノブタケ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"井上, 貴昭","creatorNameLang":"ja"},{"creatorName":"INOUE, Yoshiaki","creatorNameLang":"en"},{"creatorName":"イノウエ, ヨシアキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-01-19"}],"displaytype":"detail","filename":"Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury.pdf","filesize":[{"value":"683 KB"}],"format":"application/pdf","licensetype":"license_3","url":{"url":"https://jrckicn.repo.nii.ac.jp/record/2000018/files/Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury.pdf"},"version_id":"aaad5189-db77-4d64-a525-8d84a9773c78"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"acute physiology and chronic health evaluation II score","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"deep sedation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intensive care unit","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"tidal volume","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ventilator","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ventilator-induced lung injury","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"14","path":["15"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-01-19"},"publish_date":"2024-01-19","publish_status":"0","recid":"2000018","relation_version_is_last":true,"title":["Early Light Sedation Increased the Duration of Mechanical Ventilation in Patients With Severe Lung Injury"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2024-01-19T07:53:26.247181+00:00"}