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oai:jrckicn.repo.nii.ac.jp:00000216 2023-12-19T07:02:57Z 2

血友病の臨床 Clinical observations of hemophilia YOSHIOKA, Keiichiro 吉岡, 慶一郎 ヨシオカ, ケイイチロウ KITA, Etsuko 喜多, 悦子 キタ, エツコ FUROUCHI, Takashi 風呂内, 充 フロウチ, タケシ KITAWAKI, Tatsuo 北脇, 達雄 キタワキ, タツオ KAWAHARA, Koji 川原, 浩二 カワハラ, コウジ AMAKAWA, Yoshie 尼川, 佳江 アマカワ, ヨシエ IRIE, Akiko 入江, 章子 イリエ, アキコ application/pdf Clinical and laboratory studies were established on 7 cases with hemophilia A and 2 cases with hemophilia B. 1) The age of the patients in the first visit to our clinic were less than 5 years old, except for one case. The age of their initial hemorrhagic manifestaticns appeared between 2 weeks and 11 months. Hemarthrosis, ecchymosis, oral bleeding and excessive bleeding after trauma were common manifestations in both types of hemophilia. 2) Family history were examined in three generations. Four patients of hemophilia A and one patient of hemophilia B showed sex linked recessive transmission and another cases occured sporadically. 3) The tests for the diagnosis of hemophilia were carried out as follows: a) Routine test. Clotting time, bleeding time, platelet cell count, prothrombin time and partial thromboplastin time, b) Identification tests, thromboplastin generation test and assay of factor VIII or factor IX. Bleeding time, platelet cell count and prothrombin time in all cases of hemophilia A and B were within normal range and partial thromboplastin time was markedly prolonged. Clotting time of 5 cases with hemophilia A revealed over 60 minutes and factor VIII level showed 0 per cent. Two cases of clinically mild type showed moderate prolongation of clotting time (20 to 25 minutes) and 4-6 per cent of factor VIII. Two cases with hemo-philia B were clinically severe and their factor I revealed lower than 2 per cent. journal article 国立医療学会 1970-02 VoR 医療 2 24 95 103 Japanese journal of National Medical Services AN00017113 00211699 https://jrckicn.repo.nii.ac.jp/records/216 jpn info:doi/10.11261/iryo1946.24.95 一般社団法人国立医療学会 https://www.nhocrc.jp/iryo/gakkai.htm 医療(J-STAGE) https://www.jstage.jst.go.jp/browse/iryo1946/24/2/_contents/-char/ja/ isVersionOf:http://japanlinkcenter.org/JST.Journalarchive/iryo1946/24.95 ©1970 一般社団法人国立医療学会 本文データは学協会の許諾に基づきJ-STAGEから複製したものである